Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600694 | 0.88 | KAT6A (0.39) | EPHX2KMT2AMTNR1A | |
| SCHEMBL11598774 | 0.86 | EPHX2 (0.41) | LMNAEPHX2HPGDSMN1; SMN2RAB9A | |
| SCHEMBL11598835 | 0.86 | MAPK1 (0.48) | LMNAMAPK1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL11602076 | 0.82 | MAPK1 (0.42) | LMNAMAPK1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL11600122 | 0.82 | RARB (0.38) | ALDH1A1KDM4E | |
| SCHEMBL11598817 | 0.79 | HTT (0.41) | LMNAMAPK1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL11621403 | 0.78 | HCRTR1 (0.45) | LMNAMAPK1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL11600640 | 0.77 | KAT6A (0.44) | EPHX2NPC1MEN1KMT2A | |
| SCHEMBL11600699 | 0.76 | MAPK1 (0.46) | LMNAMAPK1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL11602118 | 0.73 | UBE2N (0.44) | SMN1; SMN2RAB9AALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |