Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602342 | 0.90 | KAT6A (0.43) | KAT6AOPRK1MEN1KMT2AEPHX2 | |
| SCHEMBL11600694 | 0.89 | KAT6A (0.39) | KAT6AKMT2AEPHX2PDE4APDE4B | |
| SCHEMBL11598774 | 0.88 | EPHX2 (0.41) | MEN1KMT2AEPHX2KCNH2NPC1 | |
| SCHEMBL11600610 | 0.84 | LTA4H (0.44) | — | |
| SCHEMBL11600699 | 0.80 | MAPK1 (0.46) | KAT6AMEN1KMT2ANPC1 | |
| SCHEMBL11599769 | 0.80 | HTT (0.34) | MEN1KMT2ANPC1 | |
| SCHEMBL11600447 | 0.78 | CA12 (0.41) | MEN1KMT2ANPC1 | |
| SCHEMBL11600101 | 0.77 | KAT6A (0.45) | KAT6AOPRK1MEN1KMT2AEPHX2 | |
| SCHEMBL11600522 | 0.77 | LMNA (0.39) | MEN1KMT2AEPHX2NPC1 | |
| SCHEMBL11622037 | 0.76 | KAT6A (0.46) | KAT6AOPRK1MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |