Toluene

Toluene

SCHEMBL11600656

CC1=C(C)CC=C1.Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.50
LMNA P02545 2/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50
HPGD P15428 1/20 0.33
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
POLB P06746 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216231 0.83
SCHEMBL9142119 0.80
SCHEMBL7263423 0.80
SCHEMBL9299246 0.80
SCHEMBL9705999 0.80
Toluene SCHEMBL175861 0.71 ACHE (1.00) ACHELMNATSHRALOX12HPGD
SCHEMBL12344943 0.71 ACHE (1.00) ACHELMNATSHRALOX12HPGD
Toluene SCHEMBL1 0.71
Toluene SCHEMBL4535818 0.71 ACHE (1.00) ACHELMNATSHRALOX12HPGD
Toluene SCHEMBL8938900 0.71 ACHE (1.00) ACHELMNATSHRALOX12HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4129605-A EXTRACTIVE DISTILLATION PHILLIPS PETROLEUM COMPANY (US) 1978-12-12 US disclosed