Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631432 | 0.87 | PRSS1 (0.55) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL7623360 | 0.82 | PRSS1 (0.58) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL2551013 | 0.77 | PRSS1 (0.50) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL44568 | 0.77 | PRSS1 (0.62) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL43233 | 0.77 | PRSS1 (0.67) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL10575704 | 0.76 | PRSS1 (0.49) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL25297232 | 0.75 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL21879662 | 0.75 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL20564639 | 0.75 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL1531270 | 0.75 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4120845-A | FOR VINYL OR VINYLIDENE HALIDE POLYMERS | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1978-10-17 | — | — | US | disclosed |