Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 14/20 | 0.72 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.72 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etiproston SCHEMBL11602088 | 0.89 | PTGFR (0.67) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| Etiproston SCHEMBL12495605 | 0.89 | PTGFR (0.67) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| Etiproston SCHEMBL11603831 | 0.89 | PTGFR (0.67) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| Etiproston SCHEMBL571117 | 0.89 | PTGFR (0.67) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| Etiproston SCHEMBL11602481 | 0.89 | PTGFR (0.67) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| Etiproston SCHEMBL12495609 | 0.89 | PTGFR (0.67) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| Lanproston SCHEMBL2109085 | 0.88 | PTGFR (0.70) | PTGFRPTGER3TBXA2RABCC4ABCB11 | |
| SCHEMBL11603828 | 0.86 | PTGFR (0.57) | PTGFRPTGER3TBXA2RABCC4PTGER1 | |
| SCHEMBL11603623 | 0.86 | PTGFR (0.57) | PTGFRPTGER3TBXA2RABCC4PTGER1 | |
| SCHEMBL11601015 | 0.85 | PTGFR (0.57) | PTGFRPTGER3TBXA2RPTGER1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088775-A | PROSTAGLANDINS WITH LONG LASTING ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | claimed |
| US-4088775-A | PROSTAGLANDINS WITH LONG LASTING ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |