Lanproston

Lanproston

SCHEMBL2109085

O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/C2(COc3cccc(Cl)c3)OCCO2)[C@H](O)C[C@@H]1O

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PTGFR P43088 16/20 0.70
▸ PTGER3 P43115 5/20 0.70
▸ TBXA2R P21731 3/20 0.70
▸ PTGER1 P34995 2/20 0.70
▸ THRB P10828 1/20 0.70
▸ PTGER2 P43116 1/20 0.70
▸ ABCC4 O15439 2/20 0.60
▸ ABCB11 O95342 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etiproston SCHEMBL12495609 0.91 PTGFR (0.67) PTGFRPTGER3TBXA2RPTGER1THRB
Etiproston SCHEMBL11603831 0.91 PTGFR (0.67) PTGFRPTGER3TBXA2RPTGER1THRB
Etiproston SCHEMBL11602088 0.91 PTGFR (0.67) PTGFRPTGER3TBXA2RPTGER1THRB
Etiproston SCHEMBL11602481 0.91 PTGFR (0.67) PTGFRPTGER3TBXA2RPTGER1THRB
Etiproston SCHEMBL571117 0.91 PTGFR (0.67) PTGFRPTGER3TBXA2RPTGER1THRB
Etiproston SCHEMBL12495605 0.91 PTGFR (0.67) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL11602425 0.90 PTGFR (0.57) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL11602885 0.90 PTGFR (0.57) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL11601421 0.88 PTGFR (0.72) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL11603828 0.88 PTGFR (0.57) PTGFRPTGER3TBXA2RPTGER1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 — — US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 — — EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 — — WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 — — US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 — — US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 — — US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 — — US disclosed
US-20140154313-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2014-06-05 — — US disclosed
EP-2717860-A1 CONTROLLED ABSORPTION WATER-SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUND FORMULATION FOR ONCE-DAILY ADMINISTRATION STI Pharma, LLC (US) 2014-04-16 — — EP disclosed
WO-2012170676-A1 CONTROLLED ABSORPTION WATER-SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUND FORMULATION FOR ONCE-DAILY ADMINISTRATION STI PHARMA, LLC (US) 2012-12-13 — — WO disclosed
US-8158152-B2 Preparing lyophilizates, especially those free of undesired extra components such as mono- or disaccharides; dosage forms of a wide variety of over 2000 drugs, such as rapidly dissolving tablets SCIDOSE LLC (US) 2012-04-17 — — US disclosed
US-7905852-B2 Skin-contacting-adhesive free dressing JENNINGS-SPRING BARBARA 2011-03-15 — — US disclosed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US disclosed
WO-2010024870-A1 SKIN-CONTACTING-ADHESIVE FREE DRESSING JENNINGS-SPRING BARBARA BROOKE (US) 2010-03-04 — — WO disclosed
US-20090005722-A1 Skin-contacting-adhesive free dressing JENNLNGS-SPRING BARBARA 2009-01-01 — — US disclosed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 — — EP disclosed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 — — WO disclosed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US disclosed
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