Phenol

Phenol

SCHEMBL1160148

CC(C)(C)c1ccc(O)c(C(C)(C)C)c1.CC(C)(C)c1ccc(O)cc1.CC(C)(C)c1ccccc1O.Oc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
TSHR P16473 4/20 0.56
TDP1 Q9NUW8 2/20 0.56
ALOX15 P16050 3/20 0.53
HSD17B10 Q99714 3/20 0.53
LMNA P02545 2/20 0.53
TYR P14679 2/20 0.53
CYP2C9 P11712 2/20 0.53
NR1I2 O75469 1/20 0.53
MIF P14174 1/20 0.53
HTT P42858 1/20 0.53
NFE2L2 Q16236 1/20 0.53
MAPT P10636 3/20 0.46
GAA P10253 2/20 0.46
MEN1 O00255 1/20 0.46
PKM P14618 1/20 0.46
RECQL P46063 1/20 0.46
KMT2A Q03164 1/20 0.46
HPGD P15428 2/20 0.46
ESR1 P03372 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL6686964 0.92 ALDH1A1 (0.57) ALDH1A1TSHRTDP1ALOX15HSD17B10
SCHEMBL27578638 0.90 ALDH1A1 (0.69) ALDH1A1TSHRTDP1ALOX15HSD17B10
P-Cresol SCHEMBL27725601 0.89 CYP1A2 (0.54) ALDH1A1TSHRTDP1ALOX15HSD17B10
SCHEMBL25385823 0.88 ALDH1A1 (0.67) ALDH1A1TSHRTDP1ALOX15HSD17B10
SCHEMBL9629444 0.86 ALDH1A1 (0.51) ALDH1A1TSHRTDP1ALOX15HSD17B10
Benzene SCHEMBL28155736 0.85 ALDH1A1 (0.61) ALDH1A1TSHRTDP1ALOX15HSD17B10
Toluene SCHEMBL28825155 0.83 ALDH1A1 (0.53) ALDH1A1TSHRTDP1ALOX15HSD17B10
Phenol SCHEMBL6238567 0.83 ALDH1A1 (0.82) ALDH1A1TSHRTDP1ALOX15HSD17B10
Biphenyl SCHEMBL28492519 0.82 ALDH1A1 (0.53) ALDH1A1TSHRTDP1ALOX15HSD17B10
Biphenyl SCHEMBL28011227 0.82 ALDH1A1 (0.53) ALDH1A1TSHRTDP1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011014209-A1 LIQUID AMYLARYL PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
WO-2011014212-A1 LIQUID BUTYLARYL PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed