SCHEMBL1160149

SCHEMBL1160149

C=CC(=O)Oc1c(CCc2cc(C(C)(C)CC)cc(C(C)(C)CC)c2O)cc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RXRA P19793 5/20 0.36
PPARG P37231 5/20 0.36
RARG P13631 4/20 0.36
THRB P10828 3/20 0.34
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
THRA P10827 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29842995 1.00 RXRA (0.36) RXRAPPARGRARGTHRBRARA
SCHEMBL2612511 0.91 RXRA (0.36) RXRAPPARGRARGTHRBRARA
SCHEMBL30123296 0.88 RXRA (0.40) RXRAPPARGRARGTHRBRARA
SCHEMBL9448615 0.84 RXRA (0.36) RXRAPPARGRARGRARARARB
SCHEMBL27242779 0.83 RXRA (0.38) RXRAPPARGRARGTHRBRARA
SCHEMBL2706073 0.83 HSPA5 (0.40) RXRAPPARGRARGSMN1; SMN2
SCHEMBL12856180 0.82 RXRA (0.34) RXRAPPARGRARGRARARARB
SCHEMBL9657298 0.82 GAA (0.38) THRBALDH1A1MAPK1NPSR1
SCHEMBL7191459 0.81 RXRA (0.36) RXRAPPARGRARGTHRBRARA
SCHEMBL17471442 0.81 RXRA (0.41) RXRAPPARGRARGTHRBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1394204-A1 BLOCK COPOLYMER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2004-03-03 EP claimed
EP-0500323-A2 Production of bisphenol monoester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-08-26 EP claimed
US-20250236727-A1 THERMOPLASTIC RESIN COMPOSITION, METHOD OF PREPARING THE SAME, AND MOLDED ARTICLE INCLUDING THE SAME LG CHEM, LTD. (KR) 2025-07-24 US disclosed
US-20250197621-A1 THERMOPLASTIC RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2025-06-19 US disclosed
US-20250051564-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 2025-02-13 US disclosed
US-12060453-B2 Polyester carbonate resin, and molded body which is obtained by molding resin composition containing resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-08-13 US disclosed
US-20240254282-A1 THERMOPLASTIC RESIN COMPOSITION, COMMUNICATION DEVICE MEMBER, AND MICROWAVE AND/OR MILLIMETER WAVE COMMUNICATION DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2024-08-01 US disclosed
WO-2024135577-A1 STABLE DISPERSION COMPOSITION COMPRISING RETINOID L'OREAL (FR) 2024-06-27 WO disclosed
WO-2023249852-A1 IONOMER RESIN COMPOSITION TREANOR, Richard (US) 2023-12-28 WO disclosed
WO-2023249122-A1 STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME L'OREAL (FR) 2023-12-28 WO disclosed
WO-2023249853-A1 IONOMER RESIN COMPOSITION KURARAY AMERICA, INC. (US) 2023-12-28 WO disclosed
WO-2011014210-A2 LIQUID PHOSPHITE COMPOSITIONS HAVING DIFFERENT ALKYL GROUPS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
WO-2011014477-A1 LIQUID ALKYLATED TRISARYL PHOSPHITE COMPOSITIONS HAVING TWO ALKYL GROUPS WITH DIFFERENT CARBON NUMBER CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
US-7781534-B2 Process for producing vinyl polymer, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2010-08-24 US disclosed
US-20090143517-A1 Bisphenol Monoester compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 US disclosed
US-20080160621-A1 Process for producing vinyl polymer, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2008-07-03 US disclosed
WO-2006047665-A1 COMPOSITION COMPRISING A MONOVINYLARENE-CONJUGATED DIENE COPOLYMER AND AN ACRYLATE TERPOLYMER AND SHRINK FILMS MADE THEREOF CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2006-05-04 WO disclosed
EP-1033243-B1 Aromatic polycarbonate resin coextruded article ASAHI DENKA KOGYO KK (JP) 2002-06-12 EP disclosed
US-6333114-B1 WEATHERABILITY AND IMPROVED COLORING RESISTANCE; FOR PRODUCING MOLDED ARTICLES SUCH AS FOOD PACKAGING CONTAINERS, INTERIOR AND EXTERIOR AUTOMOTIVE TRIM PARTS, AND PRECISION MACHINES, FILMS ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2001-12-25 US disclosed
EP-1033243-A1 Aromatic polycarbonate resin coextruded article ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2000-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090143517-A1 Bisphenol Monoester compound CYP19A1, ESR1, ESRRA RXRA 104/4885PPARG 121/4885RARG 233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.