SCHEMBL11601650

SCHEMBL11601650

Clc1ccc2nc(OCC(Cl)(Cl)Cl)nnc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.47
NR4A2 P43354 1/20 0.34
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
F7 P08709 1/20 0.33
F3 P13726 1/20 0.33
DYRK1A Q13627 1/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAT2A P31153 1/20 0.33
PIK3R1 P27986 1/20 0.33
PIK3CA P42336 1/20 0.33
CHEK1 O14757 1/20 0.33
LIMK1 P53667 1/20 0.33
MAPK14 Q16539 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11599594 0.81 PIK3CG (0.50) PIK3CGNR4A2MAPTMEN1KMT2A
SCHEMBL11602557 0.79 PIK3CG (0.49) PIK3CGNR4A2MAPTMEN1KMT2A
SCHEMBL11601656 0.78 PIK3CG (0.47) PIK3CGMAPTMEN1KMT2AF7
SCHEMBL11603303 0.77 PIK3CG (0.46) PIK3CGNR4A2MAPTMEN1KMT2A
SCHEMBL11602708 0.77 PIK3CG (0.46) PIK3CGNR4A2MAPTMEN1KMT2A
SCHEMBL11601596 0.77 PIK3CG (0.46) PIK3CGMEN1KMT2AALDH1A1HSD17B10
SCHEMBL11602126 0.75 PIK3CG (0.55) PIK3CGMAPTMEN1KMT2AF7
SCHEMBL11603861 0.75 PDE2A (0.45) PIK3CGMEN1KMT2A
SCHEMBL11601773 0.74 RAB9A (0.32) MAT2ARAB9ATDP1
SCHEMBL11600478 0.71 PIK3CG (0.50) PIK3CGMAPTMEN1KMT2AF7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4067981-A FUNGICIDES, BACTERICIDES, INSECTICIDES, ACARICIDES BAYER AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed