SCHEMBL11601686

SCHEMBL11601686

CN(C)C(=O)C(Cl)(Cl)CCl

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
DRD4 P21917 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3244472 0.79 ALDH1A1 (0.36) ALDH1A1TSHRTDP1
SCHEMBL11621506 0.74 ALDH1A1 (0.36) ALDH1A1TSHRDRD4OPRM1DRD3
SCHEMBL334822 0.71
Methyl Alcohol SCHEMBL5264660 0.69 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
SCHEMBL3615383 0.69
SCHEMBL10712669 0.67 TSHR (0.33) ALDH1A1TSHR
SCHEMBL10716641 0.67
SCHEMBL134598 0.65
SCHEMBL5348464 0.65 ALDH1A1 (0.37) ALDH1A1TSHRDRD4OPRM1DRD3
SCHEMBL19893762 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4111933-A PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION BAYER AKTIENGESELLSCHAFT (DE) 1978-09-05 US disclosed