Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601331 | 0.78 | EGFR (0.37) | EGFRPOLBLMNAEPHX1MEN1 | |
| SCHEMBL1700981 | 0.73 | EGFR (0.54) | EGFRPOLBLMNAEPHX1MEN1 | |
| SCHEMBL6139449 | 0.73 | — | — | |
| SCHEMBL2534565 | 0.73 | EGFR (0.54) | EGFRPOLBLMNAEPHX1MEN1 | |
| SCHEMBL8183701 | 0.70 | — | — | |
| SCHEMBL11602323 | 0.70 | EGFR (0.42) | EGFRPOLBLMNAEPHX1MEN1 | |
| SCHEMBL26705 | 0.69 | — | — | |
| SCHEMBL1515475 | 0.69 | EGFR (0.41) | EGFRPOLBLMNAEPHX1MEN1 | |
| SCHEMBL11601173 | 0.68 | EGFR (0.37) | EGFRPOLBLMNAEPHX1MEN1 | |
| SCHEMBL14891860 | 0.67 | CYP2C9 (0.42) | EGFRPOLBLMNAEPHX1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111933-A | PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |