SCHEMBL2534565

SCHEMBL2534565

CC(C)(C)NC(=O)C=CC(=O)NC(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.54
LMNA P02545 1/20 0.47
EPHX1 P07099 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
POLB P06746 1/20 0.37
ALDH1A1 P00352 2/20 0.33
PTGS2 P35354 1/20 0.33
GAA P10253 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1700981 1.00 EGFR (0.54) EGFRLMNAEPHX1KMT2AMEN1
SCHEMBL6364252 0.89 EGFR (0.52) EGFRLMNAKMT2AL3MBTL1POLB
SCHEMBL7761589 0.89 EGFR (0.52) EGFRLMNAKMT2AL3MBTL1POLB
SCHEMBL6364257 0.89 EGFR (0.52) EGFRLMNAKMT2AL3MBTL1POLB
SCHEMBL6748643 0.86 EGFR (0.48) EGFRLMNAEPHX1KMT2AMEN1
SCHEMBL6552685 0.86 EGFR (0.48) EGFRLMNAEPHX1KMT2AMEN1
SCHEMBL13947388 0.86 EGFR (0.48) EGFRLMNAEPHX1KMT2AMEN1
SCHEMBL25053038 0.84 EGFR (0.47) EGFRLMNAEPHX1KMT2AMEN1
SCHEMBL13108774 0.84 EGFR (0.47) EGFRLMNAEPHX1KMT2AMEN1
SCHEMBL19669756 0.84 EGFR (0.47) EGFRLMNAEPHX1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11292861-B2 Aqueous polymer dispersion BASF SE (DE) 2022-04-05 US disclosed
US-20210292457-A1 AQUEOUS POLYMER DISPERSION BASF SE (DE) 2021-09-23 US disclosed
EP-3491029-B1 AQUEOUS POLYMER DISPERSION BASF SE (DE) 2020-05-20 EP disclosed
EP-3491029-A1 AQUEOUS POLYMER DISPERSION BASF SE (DE) 2019-06-05 EP disclosed
WO-2018019977-A1 AQUEOUS POLYMER DISPERSION BASF SE (DE) 2018-02-01 WO disclosed
EP-3263209-A1 MEMBRANES COMPRISING POLYMERIC PARTICLE LAYERS BASF SE (DE) 2018-01-03 EP disclosed
US-9382442-B2 Aqueous binder compositions BASF SE (DE) 2016-07-05 US disclosed
EP-2855579-B1 AQUEOUS BINDER COMPOSITIONS BASF SE (DE) 2016-03-16 EP disclosed
US-20150099843-A1 AQUEOUS BINDER COMPOSITIONS BASF SE (DE) 2015-04-09 US disclosed
EP-2855579-A1 AQUEOUS BINDER COMPOSITIONS BASF SE (DE) 2015-04-08 EP disclosed
WO-2013174894-A1 AQUEOUS BINDER COMPOSITIONS BASF SE (DE) 2013-11-28 WO disclosed
US-8329800-B2 Binder compositions comprising boric acid or boric acid salt BASF SE (DE) 2012-12-11 US disclosed
US-20110312240-A1 AQUEOUS BINDER COMPOSITIONS BASF SE (DE) 2011-12-22 US disclosed
US-20110257302-A1 BINDER COMPOSITIONS COMPRISING BORIC ACID OR BORIC ACID SALT BASF SE (DE) 2011-10-20 US disclosed