Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21102151 | 0.93 | PTGS2 (0.63) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL5637483 | 0.89 | SMN1; SMN2 (0.56) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL8157886 | 0.82 | PTGS2 (0.66) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL8155943 | 0.82 | PTGS2 (0.66) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL8162845 | 0.82 | PTGS2 (0.66) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL8156044 | 0.82 | PTGS2 (0.66) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL8164521 | 0.82 | PTGS2 (0.66) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL8159641 | 0.82 | PTGS2 (0.66) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL8156427 | 0.82 | PTGS2 (0.66) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL8158320 | 0.82 | PTGS2 (0.66) | ALDH1A1PTGS2SMN1; SMN2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086240-A | 1-Thiazolyl-5-phenoxy and phenylthioalkanoyloxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |
| US-4053480-A | 1-THIADIAZOLYL-5-PHENOXY- AND PHENYLTHIOALKANOYLOXY IMIDAZOLIDINONES | VELSICOL CHEMICAL CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |