Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964157 | 0.86 | FFAR4 (0.69) | FFAR4FFAR1 | |
| SCHEMBL11601264 | 0.86 | FFAR4 (0.69) | FFAR4FFAR1 | |
| SCHEMBL11602008 | 0.86 | FFAR4 (0.69) | FFAR4FFAR1 | |
| SCHEMBL11602010 | 0.86 | FFAR4 (0.69) | FFAR4FFAR1 | |
| SCHEMBL11601969 | 0.84 | FFAR4 (0.46) | KDM4CKDM4APHF8KDM2AFFAR4 | |
| SCHEMBL11730813 | 0.84 | FFAR4 (0.40) | KDM4CKDM4APHF8KDM2AFFAR4 | |
| SCHEMBL11604163 | 0.82 | ABCC4 (0.49) | FFAR4FFAR1EPHX2 | |
| SCHEMBL11603782 | 0.81 | FFAR4 (0.47) | KDM4CKDM4APHF8KDM2AFFAR4 | |
| SCHEMBL11786835 | 0.81 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AFFAR4 | |
| SCHEMBL11728631 | 0.80 | FFAR4 (0.44) | KDM4CKDM4APHF8KDM2AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091107-A | RENAL VASODILATORS, ANTICLOTTING AGENTS, GROWTH HORMONE RELEASE, REGULATORS OF IMMUNE RESPONSE | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4033996-A | RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | disclosed |