Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.69 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | PTGFR | P43088 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602008 | 1.00 | FFAR4 (0.69) | FFAR4FFAR1FAAHTBXA2RPTGFR | |
| SCHEMBL4964157 | 1.00 | FFAR4 (0.69) | FFAR4FFAR1FAAHTBXA2RPTGFR | |
| SCHEMBL11602010 | 1.00 | FFAR4 (0.69) | FFAR4FFAR1FAAHTBXA2RPTGFR | |
| SCHEMBL11602477 | 0.90 | FFAR4 (0.71) | FFAR4FFAR1FAAHTBXA2RPTGFR | |
| SCHEMBL11601442 | 0.89 | FFAR4 (0.51) | FFAR4FFAR1FAAHGPR84MEN1 | |
| SCHEMBL11603394 | 0.86 | FFAR4 (0.65) | FFAR4FFAR1FAAHTBXA2RPTGFR | |
| SCHEMBL11602705 | 0.86 | FFAR4 (0.65) | FFAR4FFAR1FAAHTBXA2RPTGFR | |
| SCHEMBL11601867 | 0.86 | KDM4C (0.49) | FFAR4FFAR1 | |
| SCHEMBL11602265 | 0.86 | ACE2 (0.51) | FFAR4FFAR1FAAHGPR84 | |
| SCHEMBL11602268 | 0.85 | L3MBTL1 (0.52) | FFAR4FFAR1FAAHGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033996-A | RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | claimed |
| US-4091107-A | RENAL VASODILATORS, ANTICLOTTING AGENTS, GROWTH HORMONE RELEASE, REGULATORS OF IMMUNE RESPONSE | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4033996-A | RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | disclosed |