Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.71 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603394 | 0.93 | FFAR4 (0.65) | FFAR4FFAR1FAAHGPR84PPARG | |
| SCHEMBL11601264 | 0.90 | FFAR4 (0.69) | FFAR4FFAR1FAAHGPR84PPARG | |
| SCHEMBL11602008 | 0.90 | FFAR4 (0.69) | FFAR4FFAR1FAAHGPR84PPARG | |
| SCHEMBL11602010 | 0.90 | FFAR4 (0.69) | FFAR4FFAR1FAAHGPR84PPARG | |
| SCHEMBL4964157 | 0.90 | FFAR4 (0.69) | FFAR4FFAR1FAAHGPR84PPARG | |
| SCHEMBL11602705 | 0.87 | FFAR4 (0.65) | FFAR4FFAR1FAAHGPR84PPARG | |
| Behenic Acid SCHEMBL28172988 | 0.86 | FFAR4 (0.96) | FFAR4FFAR1GPR84PPARGPPARD | |
| Palmitic Acid SCHEMBL28172999 | 0.86 | FFAR4 (0.96) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL25190974 | 0.84 | FFAR4 (1.00) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL22400853 | 0.84 | FFAR4 (0.92) | FFAR4FFAR1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033996-A | RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | claimed |
| US-4091107-A | RENAL VASODILATORS, ANTICLOTTING AGENTS, GROWTH HORMONE RELEASE, REGULATORS OF IMMUNE RESPONSE | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4033996-A | RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | disclosed |