Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecylamine SCHEMBL11060817 | 0.96 | LPAR3 (0.53) | LPAR3LPAR2LPAR1DNM1MEN1 | |
| Dodecylamine SCHEMBL27830346 | 0.94 | LPAR3 (0.52) | LPAR3LPAR2LPAR1DNM1MEN1 | |
| SCHEMBL7948187 | 0.93 | LPAR3 (0.64) | LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL9676047 | 0.93 | LPAR3 (0.64) | LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL1262956 | 0.93 | LPAR3 (0.64) | LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL5086025 | 0.93 | LPAR3 (0.64) | LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4436297 | 0.93 | LPAR3 (0.64) | LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL649061 | 0.93 | LPAR3 (0.64) | LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL11025774 | 0.93 | LPAR3 (0.64) | LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL5453677 | 0.93 | LPAR3 (0.64) | LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108858-A | Polyolefin quaternary pyridinium salts | ETHYL CORPORATION (US) | 1978-08-22 | — | — | US | disclosed |
| US-4065499-A | POLYALKYLENE AMMONIUM CHLORIDE | ETHYL CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4056531-A | DETERGENTS AND DISPERSANTS FOR GASOLINE AND LUBRICATING OIL | ETHYL CORPORATION (US) | 1977-11-01 | — | — | US | disclosed |