SCHEMBL649061

SCHEMBL649061

CCCCCCCCOP(=S)(S)OCCCCCCCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 15/20 0.64
LPAR2 Q9HBW0 13/20 0.64
LPAR1 Q92633 10/20 0.52
LPAR6 P43657 5/20 0.43
LPAR4 Q99677 5/20 0.43
LPAR5 Q9H1C0 5/20 0.43
CYP3A4 P08684 1/20 0.42
LMNA P02545 1/20 0.41
ESR1 P03372 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
CDC25A P30304 1/20 0.41
AGTR1 P30556 1/20 0.41
AKT1 P31749 1/20 0.41
ADRA1A P35348 1/20 0.41
KCNH2 Q12809 1/20 0.41
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26234272 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL9676047 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL6701668 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL5453677 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL5086025 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL7948187 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL1262956 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL4436297 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL11025774 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL2716235 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111875639-B Dialkyl dithio organic molybdenum and preparation method and application thereof 上海交通大学 2023-12-26 CN claimed
CN-111234899-A Organic nano friction reducing agent and preparation method and application thereof 青岛康普顿石油化工有限公司 2020-06-05 CN claimed
US-20180118675-A1 PROCESSES FOR CONVERTING CARBOXAMIDES TO THIOCARBOXAMIDES VERTELLUS HOLDINGS LLC (US) 2018-05-03 US claimed
EP-3294708-A1 PROCESSES FOR CONVERTING CARBOXAMIDES TO THIOCARBOXAMIDES Vertellus Holdings LLC (US) 2018-03-21 EP claimed
EP-1737936-B1 HYDRAULIC COMPOSITION CONTAINING A SUBSTANTIALLY NITROGEN FREE DISPERSANT LUBRIZOL CORP (US) 2017-01-25 EP claimed
WO-2016182900-A1 PROCESSES FOR CONVERTING CARBOXAMIDES TO THIOCARBOXAMIDES VERTELLUS SPECIALTIES, INC. (US) 2016-11-17 WO claimed
CN-105255547-A Preparation method of graphene functional lubricating oil DEVON ENERGY CORP 2016-01-20 CN claimed
CN-103897772-B A kind of preparation method of function lubricating oil CHONGQING DEVON LUBRICANT CO., LTD. (CN) 2015-09-02 CN claimed
CN-103897772-A Preparation method of functional lubricating oil CHONGQING DEVON LUBRICANT CO LTD 2014-07-02 CN claimed
CN-102115689-B Mine-used flame retardant gear liquid and preparation method thereof GAOBEIDIAN CHINA COAL SHENHAI TECHNOLOGY DEV CO LTD 2011-12-14 CN claimed
CN-102115689-A Mine-used flame retardant gear liquid and preparation method thereof GAOBEIDIAN CHINA COAL SHENHAI TECHNOLOGY DEV CO LTD 2011-07-06 CN claimed
EP-0770668-B1 Lubricating oil composition NIPPON MITSUBISHI OIL CORP (JP) 2001-09-05 EP claimed
US-6184296-B1 SUITABLE FOR PRODUCTION OF LOW ROLLING RESISTANCE MOTOR VEHICLE TIRE TREADS BAYER AG (DE) 2001-02-06 US claimed
US-5525248-A REACTION PRODUCT OF ORGANOTIN COMPOUND AND PHOSPHORIC ACID OR DITHIOPHOSPHORIC ACID DERIVATIVE MOBIL OIL CORPORATION (US) 1996-06-11 US claimed
US-5258130-A Reaction product of a hydrocarbon substituted phosphoric acid, hydrocarbon substituted succinic anhydride and a hydrocarbon substituted organotin compound MOBIL OIL CORPORATION (US) 1993-11-02 US claimed
EP-0208541-B1 LUBRICANT COMPOSITIONS NIPPON OIL CO. LTD. (JP) 1991-12-04 EP claimed
CN-86100205-A Rubber combination 1986-08-13 CN claimed
JP-62250096-A None JP disclosed
US-3957854-A FUEL ADDITIVES, LUBRICANTS THE LUBRIZOL CORPORATION (US) 1976-05-18 US disclosed
US-3957855-A FUEL ADDITIVES, LUBRICANTS THE LUBRIZOL CORPORATION (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118675-A1 PROCESSES FOR CONVERTING CARBOXAMIDES TO THIOCARBOXAMIDES CPS1, DCTD, TPMT LPAR3 4627/4885LPAR2 4526/4885LPAR1 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.