SCHEMBL11604652

SCHEMBL11604652

O=C(O)C(CN1CCOCC1)CN1CCOCC1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.63
USP2 O75604 1/20 0.56
LMNA P02545 3/20 0.54
MAPT P10636 3/20 0.54
ATM Q13315 2/20 0.54
HTT P42858 1/20 0.54
RAB9A P51151 1/20 0.54
HIF1A Q16665 1/20 0.54
HSD17B10 Q99714 2/20 0.52
ANPEP P15144 1/20 0.48
GLA P06280 1/20 0.48
KDM4E B2RXH2 2/20 0.47
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
NPC1 O15118 1/20 0.43
HSP90AA1 P07900 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12541627 0.88 ALDH1A1 (0.56) ALDH1A1USP2LMNAMAPTATM
SCHEMBL500355 0.88 ALDH1A1 (0.61) ALDH1A1USP2LMNAMAPTATM
SCHEMBL2027547 0.85 ALDH1A1 (0.53) ALDH1A1USP2LMNAMAPTATM
SCHEMBL7371485 0.85 ALDH1A1 (0.57) ALDH1A1USP2LMNAMAPTATM
SCHEMBL499959 0.82 ALDH1A1 (0.54) ALDH1A1USP2LMNAMAPTATM
SCHEMBL12227732 0.82 ALDH1A1 (0.54) ALDH1A1USP2LMNAMAPTATM
SCHEMBL500328 0.81 ALDH1A1 (0.53) ALDH1A1USP2LMNAMAPTATM
SCHEMBL31757733 0.81 ALDH1A1 (0.61) ALDH1A1USP2LMNAMAPTATM
SCHEMBL15049655 0.81 ALDH1A1 (0.61) ALDH1A1USP2LMNAMAPTATM
SCHEMBL5533637 0.81 ALDH1A1 (0.61) ALDH1A1USP2LMNAMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1616897-B1 Novel polymeric co-initiators AGFA GRAPHICS NV (BE) 2010-03-31 EP disclosed
EP-1616899-B1 Novel photoreactive polymers AGFA GRAPHICS NV (BE) 2010-03-24 EP disclosed
EP-1674499-B1 Radiation curable compositions AGFA GRAPHICS NV (BE) 2009-12-16 EP disclosed
US-7538144-B2 Photoreactive polymers AGFA GRAPHICS, N.V. (BE) 2009-05-26 US disclosed
US-7538144-B2 Photoreactive polymers AGFA GRAPHICS, N.V. (BE) 2009-05-26 US disclosed
US-7507773-B2 Dendritic polymer core, e.g., hyperbranched polyglycidol, with at least one initiating functional group and at least one co-initiating functional group that is an aliphatic amine, an aromatic amine or a thiol; ink jet inks AGFA GRAPHICS N.V. (BE) 2009-03-24 US disclosed
US-7507773-B2 Dendritic polymer core, e.g., hyperbranched polyglycidol, with at least one initiating functional group and at least one co-initiating functional group that is an aliphatic amine, an aromatic amine or a thiol; ink jet inks AGFA GRAPHICS N.V. (BE) 2009-03-24 US disclosed
US-7507785-B2 Polymeric co-initiators AGFA GRAPHICS N.V. (BE) 2009-03-24 US disclosed
US-7507785-B2 Polymeric co-initiators AGFA GRAPHICS N.V. (BE) 2009-03-24 US disclosed
US-7396861-B2 Containing a photoinitiator polymer with a dendritic polymer core with at least one co-initiating aliphatic amine, aromatic amine or thiol end group, e.g., a polyglycidol esterified with p-(dimethylamino)benzoic acid; ink jet inks; food packaging with reduced extractables AGFA GRAPHICS NV (BE) 2008-07-08 US disclosed
US-7396861-B2 Containing a photoinitiator polymer with a dendritic polymer core with at least one co-initiating aliphatic amine, aromatic amine or thiol end group, e.g., a polyglycidol esterified with p-(dimethylamino)benzoic acid; ink jet inks; food packaging with reduced extractables AGFA GRAPHICS NV (BE) 2008-07-08 US disclosed
EP-1616922-B1 Novel radiation curable compositions AGFA GRAPHICS NV (BE) 2007-08-29 EP disclosed
US-4086213-A FOR POLYURETHANE SYNTHESIS AIR PRODUCTS AND CHEMICALS, INC. (US) 1978-04-25 US disclosed