Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11608101 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1FABP4FABP5FABP3 | |
| SCHEMBL11610622 | 0.82 | ALDH1A1 (0.75) | KDM4EALDH1A1FABP4FABP5FABP3 | |
| SCHEMBL11610214 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1FABP4FABP5FABP3 | |
| SCHEMBL11604973 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1FABP4FABP5FABP3 | |
| SCHEMBL3322057 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1FABP4FABP5FABP3 | |
| SCHEMBL11609303 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1FABP4FABP5FABP3 | |
| SCHEMBL11602533 | 0.77 | MEN1 (0.57) | KDM4EALDH1A1FABP4FABP5SMN1; SMN2 | |
| SCHEMBL11603283 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1FABP4FABP5FABP3 | |
| SCHEMBL11606635 | 0.75 | ALDH1A1 (0.68) | KDM4EALDH1A1FABP4FABP5FABP3 | |
| SCHEMBL11603082 | 0.73 | KDM4E (0.65) | KDM4EALDH1A1FABP4FABP5FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021448-A | ANTISECRETORY AND ANTIULCER ACTIVITIES | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | claimed |
| US-4069337-A | 2-SUBSTITUTED-INDOLE-1-LOWER-ALKANECARBOXAMIDES HAVING ANTI-SECRETORY OR ANTI-ULCER ACTIVITY | STERLING DRUG INC. (US) | 1978-01-17 | — | — | US | disclosed |
| US-4021448-A | ANTISECRETORY AND ANTIULCER ACTIVITIES | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |