Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604241 | 0.87 | MAPT (0.39) | MAPTRETPI4KAXDHLRRK2 | |
| SCHEMBL2267087 | 0.74 | MAPT (0.46) | MAPTRETPI4KAXDHLRRK2 | |
| SCHEMBL24981147 | 0.73 | HTT (0.38) | MAPTMETAP2IDO1HTTPTK2 | |
| SCHEMBL11607031 | 0.73 | IDO1 (0.39) | MAPTRETPI4KAXDHLRRK2 | |
| SCHEMBL11612665 | 0.73 | MAPT (0.35) | MAPTRETPI4KAXDHLRRK2 | |
| Hydrochloric Acid SCHEMBL11609047 | 0.71 | MAPT (0.43) | MAPTRETPI4KAXDHLRRK2 | |
| SCHEMBL11609591 | 0.69 | MAPT (0.38) | MAPTRETPI4KAXDHLRRK2 | |
| SCHEMBL1482228 | 0.68 | RET (0.44) | MAPTRETPI4KAXDHLRRK2 | |
| SCHEMBL11604269 | 0.67 | MAPT (0.36) | MAPTRETPI4KAXDHLRRK2 | |
| SCHEMBL11607563 | 0.66 | MAPT (0.39) | MAPTRETPI4KAXDHLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104020-A | OXIDIZABLE DEVELOPER-COUPLER | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1978-08-01 | — | — | US | disclosed |