Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.51 |
| ▸ | GNG2 | P59768 | 1/20 | 0.49 |
| ▸ | GNB1 | P62873 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 4/20 | 0.44 |
| ▸ | FABP4 | P15090 | 4/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17029053 | 0.93 | DHODH (0.54) | MAPK1EGFRMAPTPABPC1RAB9A | |
| SCHEMBL11797516 | 0.87 | DHODH (0.55) | MAPK1EGFRMAPTPABPC1RAB9A | |
| SCHEMBL42481 | 0.84 | MAPT (0.71) | MAPK1EGFRMAPTPABPC1RAB9A | |
| SCHEMBL29438168 | 0.84 | MAPT (0.71) | MAPK1EGFRMAPTPABPC1RAB9A | |
| SCHEMBL11306687 | 0.84 | MAPT (0.71) | MAPK1EGFRMAPTPABPC1RAB9A | |
| SCHEMBL11790292 | 0.83 | FABP3 (0.48) | MAPK1EGFRMAPTPABPC1RAB9A | |
| SCHEMBL11791498 | 0.83 | CXCL8 (0.48) | MAPK1EGFRMAPTPABPC1RAB9A | |
| SCHEMBL11790953 | 0.82 | CYP1A2 (0.47) | MAPK1EGFRMAPTPABPC1RAB9A | |
| SCHEMBL10601717 | 0.81 | CYP1A2 (0.69) | MAPK1EGFRMAPTPABPC1RAB9A | |
| SCHEMBL11063817 | 0.81 | DHODH (0.60) | MAPK1EGFRMAPTPABPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128396-A | Process for the improvement of dyeing properties of pigments of the anilino and arylmercapto anthraquinone series | CIBA-GEIGY CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |
| US-3975410-A | Process for the manufacture of halogen-containing anthraquinoidal compounds, their use and new halogen-containing anthraquinoidal compounds | CIBA-GEIGY CORPORATION (US) | 1976-08-17 | — | — | US | disclosed |