CXCL8 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Acetic Acid (SCHEMBL719624)	0.56	8/20
SCHEMBL576761	0.54	8/20
SCHEMBL577375	0.53	8/20
SCHEMBL577374	0.52	8/20
SCHEMBL576889	0.52	8/20
SCHEMBL576512	0.50	8/20
SCHEMBL457991	0.51	7/20
SCHEMBL220501	0.56	6/20
SCHEMBL340105	0.51	6/20
SCHEMBL304060	0.50	6/20
4'-Hydroxy-Diclofenac (SCHEMBL155743)	0.76	5/20
SCHEMBL361662	0.67	5/20
SCHEMBL360591	0.65	5/20
SCHEMBL867945	0.54	5/20
SCHEMBL30359	0.53	5/20
SCHEMBL194382	0.53	5/20
SCHEMBL711355	0.47	5/20
SCHEMBL509855	0.47	5/20
SCHEMBL72851	0.46	5/20
SCHEMBL76036	0.46	5/20

Clinical trials — most relevant to CXCL8 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Study of Azithromycin for Lymphocytic Bronchiolitis/Bronchitis After Lung Transplantation	PHASE4	COMPLETED
Effects of Allopurinol on Inflammation and Ultrasonographic Changes in People With Elevated Uric Acid But no Symptoms	PHASE3	UNKNOWN
A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD	PHASE2	COMPLETED
Effect of IMMUNEPOTENT-CRP on Serum Pro-Inflammatory Cytokines in Mild to Moderate COVID-19	PHASE1/PHASE2	COMPLETED
Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy	PHASE1/PHASE2	RECRUITING
Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese Encephalitis	PHASE2	COMPLETED
IRon Nanoparticle Enhanced MRI in the Assessment of Myocardial infarctioN	PHASE2	COMPLETED
RP72 Monotherapy and in Combination With Gemcitabine in Patients With Pancreatic Cancer	PHASE1	UNKNOWN
A Supervised Nutritional Program in Pregnancies and NF-κB Expression in Placenta	PHASE1	COMPLETED
Curcumin/Turmeric as a Treatment for Patients With Subdural Hematomas Recurrence	EARLY_PHASE1	WITHDRAWN
IL6&8 in Malnourished Children With Acute Diarrhea	nan	UNKNOWN
Impaired Secretory IgA and Mucosal Immunity in Cystic Fibrosis	nan	UNKNOWN
Relation of IL23R and IL17A Gene Polymorphisms Plus Serum Levels of IL23 and IL17A to Rheumatoid Arthritis Susceptibility and Activity	nan	NOT_YET_RECRUITING
N/LP Ratio as Predictor of Mortality in Septic AKI Patients	nan	UNKNOWN
Building an Assessment Model for Vitiligo Activity and Prognosis Using Peripheral Blood Cytokine Profiles	nan	NOT_YET_RECRUITING
Interleukin-8 Level in Packed Red Blood Cells	nan	NOT_YET_RECRUITING
Minimally Invasive Kidney Transplantation	nan	UNKNOWN
The Changes of Cytokines in Guillain Barré Syndrome: the Correlation With Clinical Manifestations and Skin Innervation	nan	UNKNOWN
Endotoxin and Bronchial Inflammation in Asthma	nan	COMPLETED
Innate Immunity, MIcrobiota and Inovative Treatments in Endometriosis	nan	NOT_YET_RECRUITING
Evaluation of Salivary Biomarker Levels in Individuals With Different Periodontal Conditions	nan	COMPLETED
Can Soluble-CD163 Discriminate Between Healthy and Unhealthy Obese Individuals?	nan	COMPLETED
Peri-implantitis and MMP-8	nan	COMPLETED
Characterization of Pulp Inflammation: an Observational Study Using Biological Samples Collected During Routine Dental Care	nan	NOT_YET_RECRUITING
Cytokine Status of Covid-19 Patients	nan	COMPLETED
Collection of Lung Fluid and Tissue Samples for Research	nan	RECRUITING
Biomarker of Lung Injury in ARDS Patients Receiving ECMO Support	nan	UNKNOWN
Platelet-Rich Plasma Composition and Clinical Effects in Knee Osteoarthritis	nan	COMPLETED
Effects of Acupuncture Stimulation on Systemic Inflammation	nan	UNKNOWN
Observational Cross-sectional Study Aiming to Determine the Correlation Between Pulpal Status and IL-8 and Presepsin Levels in the Pulpal Blood.	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a CXCL8 binder may also engage these)

Protein	Name	Similarity
P36925	—	1.000	P36925 →
P67814	—	1.000	P67814 →
P67813	—	1.000	P67813 →
P46653	—	0.998	P46653 →
Q9XSX5	—	0.997	Q9XSX5 →
P19874	—	0.997	P19874 →
Q7YRB5	—	0.993	Q7YRB5 →
P41324	—	0.993	P41324 →
P79255	—	0.992	P79255 →
P26894	—	0.992	P26894 →
O62812	—	0.988	O62812 →
P49113	—	0.985	P49113 →
P82943	—	0.983	P82943 →
Q5KSV9	—	0.983	Q5KSV9 →
Q9QXY8	—	0.981	Q9QXY8 →
CXCL10	C-X-C motif chemokine 10	0.981	landscape →
Q9WUZ6	—	0.981	Q9WUZ6 →
Q8MIZ1	—	0.981	Q8MIZ1 →
P08317	—	0.981	P08317 →
P43030	—	0.980	P43030 →
P48973	—	0.979	P48973 →
Q2KIQ8	—	0.979	Q2KIQ8 →
PF4	Platelet factor 4	0.979	landscape →
Q102R3	—	0.978	Q102R3 →
P10720	—	0.978	P10720 →
P22952	—	0.978	P22952 →
Q9Z126	—	0.976	Q9Z126 →
Q09141	—	0.976	Q09141 →
Q03366	—	0.975	Q03366 →
P17515	—	0.975	P17515 →