Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 8/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954320 | 0.90 | NPC1 (0.81) | BCHENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL24596471 | 0.84 | NPC1 (0.72) | BCHENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL708285 | 0.84 | NPC1 (0.72) | BCHENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL87505 | 0.84 | NPC1 (0.71) | BCHENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL29371290 | 0.84 | NPC1 (0.71) | BCHENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28852479 | 0.83 | BCHE (0.71) | BCHENPC1RAB9ASMN1; SMN2MAPT | |
| Water SCHEMBL27478798 | 0.82 | NPC1 (0.69) | BCHENPC1RAB9ASMN1; SMN2MAPT | |
| Water SCHEMBL5134592 | 0.82 | NPC1 (0.69) | BCHENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28165461 | 0.81 | BCHE (0.68) | BCHENPC1RAB9ASMN1; SMN2AR | |
| SCHEMBL708043 | 0.81 | NPC1 (1.00) | BCHENPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061762-B | Side chain-bisphenol type quinoxalinyl benzoxazine resin | 哈尔滨工程大学 | 2017-04-12 | — | — | CN | disclosed |
| CN-105061762-A | Side chain-bisphenol type quinoxalinyl benzoxazine resin | UNIV HARBIN ENG | 2015-11-18 | — | — | CN | disclosed |
| US-8569295-B2 | Bicyclic urea compounds | MERCK PATENT GMBH (DE) | 2013-10-29 | — | — | US | disclosed |
| EP-2461869-B1 | NOVEL BICYCLIC UREA COMPOUNDS | MERCK PATENT GMBH (DE) | 2013-08-21 | — | — | EP | disclosed |
| US-20120190654-A1 | NOVEL BICYCLIC UREA COMPOUNDS | MERCK PATENT GMBH (DE) | 2012-07-26 | — | — | US | disclosed |
| EP-2461869-A1 | NOVEL BICYCLIC UREA COMPOUNDS | Merck Patent GmbH (DE) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017142-A1 | NOVEL BICYCLIC UREA COMPOUNDS | MERCK PATENT GMBH (DE) | 2011-02-10 | — | — | WO | disclosed |
| CN-1006386-B | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | SHINETSU CHEM IND CO (JP) | 1990-01-10 | — | — | CN | disclosed |
| CN-85107531-A | Process for producing vinyl chloride polymer | — | 1987-01-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190654-A1 | NOVEL BICYCLIC UREA COMPOUNDS | CCNC, CCNI, CCNA1 | BCHE 2031/4885NPC1 1489/4885RAB9A 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.