Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238950 | 0.85 | CARM1 (0.66) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7322124 | 0.85 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL5568520 | 0.84 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL7294981 | 0.82 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL7362469 | 0.81 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL13450806 | 0.80 | KCNH2 (0.60) | — | |
| Hydrochloric Acid SCHEMBL7356651 | 0.79 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL466899 | 0.79 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL9372865 | 0.79 | SIGMAR1 (0.49) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7295872 | 0.78 | TMEM97 (0.69) | SIGMAR1HTR1ADRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086347-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS, HYPOTENSIVES | BOEHRINGER MANNHEIM GMBH (DT) | 1978-04-25 | — | — | US | disclosed |