⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2746559 | 0.82 | CRBN (0.52) | — | |
| SCHEMBL9635955 | 0.79 | CRBN (0.53) | — | |
| SCHEMBL22100322 | 0.78 | CRBN (0.48) | — | |
| SCHEMBL6021242 | 0.78 | TDP1 (0.60) | — | |
| SCHEMBL4410041 | 0.77 | — | — | |
| Diacetamide SCHEMBL4953257 | 0.76 | CRBN (0.69) | — | |
| SCHEMBL25878964 | 0.75 | CRBN (0.44) | — | |
| SCHEMBL28740940 | 0.73 | — | — | |
| SCHEMBL1696471 | 0.73 | — | — | |
| SCHEMBL29286885 | 0.73 | CRBN (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227465-B2 | Combination of triazine derivatives and insulin secretion stimulators | POXEL SAS (FR) | 2012-07-24 | — | — | US | claimed |
| US-20100233255-A1 | COMBINATION OF TRAZINE DERIVATIVES AND INSULIN SECRETION STIMULATORS | POXEL SAS (FR) | 2010-09-16 | — | — | US | claimed |
| EP-1971339-A2 | COMBINATION OF TRIAZINE DERIVATIVES AND INSULIN SECRETION STIMULATORS | Merck Patent GmbH (DE) | 2008-09-24 | — | — | EP | claimed |
| WO-2007079914-A2 | COMBINATION OF TRIAZINE DERIVATIVES AND INSULIN SECRETION STIMULATORS | MERCK PATENT GMBH (DE) | 2007-07-19 | — | — | WO | claimed |
| JP-1207289-A | — | — | None | — | — | JP | disclosed |
| CN-110849994-B | Method for separating related substances in rivaroxaban | 湖南九典制药股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| EP-2459555-B1 | PROCESSES FOR CRYSTALLIZATION OF RIVAROXABAN | KRKA D D NOVO MESTO (SI) | 2021-11-03 | — | — | EP | disclosed |
| CN-107250127-B | Herbicidal compounds | 先正达参股股份有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-106715425-B | Herbicidal quinolines | 先正达参股股份有限公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-107257799-B | Triazolotriazinone derivatives having activity as herbicides | 先正达参股股份有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-110849994-A | Method for separating related substances in rivaroxaban | 湖南九典制药股份有限公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-104193737-B | A kind of synthetic method of razaxaban impurity | 吉林省东盟制药有限公司 | 2016-07-06 | — | — | CN | disclosed |
| US-8227465-B2 | Combination of triazine derivatives and insulin secretion stimulators | POXEL SAS (FR) | 2012-07-24 | — | — | US | disclosed |
| EP-2459555-A1 | PROCESSES FOR CRYSTALLIZATION OF RIVAROXABAN | KRKA, D.D., Novo Mesto (SI) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011012321-A1 | PROCESSES FOR CRYSTALLIZATION OF RIVAROXABAN | KRKA, D.D., NOVO MESTO (SI) | 2011-02-03 | — | — | WO | disclosed |
| US-20100233255-A1 | COMBINATION OF TRAZINE DERIVATIVES AND INSULIN SECRETION STIMULATORS | POXEL SAS (FR) | 2010-09-16 | — | — | US | disclosed |
| CN-101355949-A | Combination of triazine derivatives and insulin secretion enhancers | MERCK PATENT GMBH (DE) | 2009-01-28 | — | — | CN | disclosed |
| EP-1971339-A2 | COMBINATION OF TRIAZINE DERIVATIVES AND INSULIN SECRETION STIMULATORS | Merck Patent GmbH (DE) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007079914-A2 | COMBINATION OF TRIAZINE DERIVATIVES AND INSULIN SECRETION STIMULATORS | MERCK PATENT GMBH (DE) | 2007-07-19 | — | — | WO | disclosed |
| JP-H01207289-A | PRODUCTION OF ACYLAMINOACETONITRILE DERIVATIVE | MITSUI TOATSU CHEM INC | 1989-08-21 | — | — | JP | disclosed |