Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL632939 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL31670321 | 0.88 | — | — | |
| Bicarbonate SCHEMBL18789077 | 0.88 | — | — | |
| Bicarbonate SCHEMBL31364693 | 0.88 | — | — | |
| Bicarbonate SCHEMBL14562512 | 0.88 | — | — | |
| Bicarbonate SCHEMBL1004629 | 0.88 | CA4 (0.46) | CA4CA1FAHD1FFAR3HDAC3 | |
| Bicarbonate SCHEMBL15104746 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15104745 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1020517 | 0.88 | CA4 (0.46) | CA4CA1FAHD1FFAR3HDAC3 | |
| Bicarbonate SCHEMBL5052082 | 0.88 | CA4 (0.46) | CA4CA1FAHD1FFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11047022-B2 | Processes for the recovery of uranium from wet-process phosphoric acid using dual or single cycle continuous ion exchange approaches | OCP S.A. (MA) | 2021-06-29 | — | — | US | disclosed |
| US-20190078176-A1 | PROCESSES FOR THE RECOVERY OF URANIUM FROM WET-PROCESS PHOSPHORIC ACID USING DUAL OR SINGLE CYCLE CONTINUOUS ION EXCHANGE APPROACHES | K-TECHNOLOGIES, INC. (US) | 2019-03-14 | — | — | US | disclosed |
| US-10060011-B2 | Processes for the recovery of uranium from wet-process phosphoric acid using dual or single cycle continuous ion exchange approaches | K-TECHNOLOGIES, INC. (US) | 2018-08-28 | — | — | US | disclosed |
| US-20170335430-A1 | Processes for the Recovery of Uranium from Wet-Process Phosphoric Acid Using Dual or Single Cycle Ion Exchange Approaches | K-TECHNOLOGIES, INC. (US) | 2017-11-23 | — | — | US | disclosed |
| US-9702026-B2 | Processes for the recovery of uranium from industrial phosphoric acid using dual or single cycle continuous ion exchange approaches | K-TECHNOLOGIES, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-20150203939-A1 | PROCESSES FOR THE RECOVERY OF URANIUM FROM WET-PROCESS PHOSPHORIC ACID USING DUAL OR SINGLE CYCLE ION EXCHANGE APPROACHES | OCP S.A. (MA) | 2015-07-23 | — | — | US | disclosed |
| WO-2014018422-A1 | PROCESSES FOR THE RECOVERY OF URANIUM FROM WET-PROCESS PHOSPHORIC ACID USING A SINGLE DUAL OR DUAL SINGLE CYCLE ION EXCHANGE APPROACHES | K-TECHNOLOGIES, INC. (US) | 2014-01-30 | — | — | WO | disclosed |
| US-8636966-B2 | Compositions and methods for treating nuclear fuel | BATTELLE MEMORIAL INSTITUTE (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130336854-A1 | COMPOSITIONS AND METHODS FOR TREATING NUCLEAR FUEL | BATTELLE MEMORIAL INSTITUTE (US) | 2013-12-19 | — | — | US | disclosed |
| US-8506911-B2 | Compositions and methods for treating nuclear fuel | BATTELLE MEMORIAL INSTITUTE (US) | 2013-08-13 | — | — | US | disclosed |
| WO-2011016916-A2 | COMPOSITIONS AND METHODS FOR TREATING NUCLEAR FUEL | BATTELLE MEMORIAL INSTITUTE (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20110024704-A1 | Compositions and Methods for Treating Nuclear Fuel | U.S. DEPARTMENT OF ENERGY | 2011-02-03 | — | — | US | disclosed |