Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL30978805 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5733658 | 0.94 | CA4 (0.42) | CA4CA1FAHD1FFAR3HDAC3 | |
| Bicarbonate SCHEMBL7111306 | 0.94 | CA4 (0.42) | CA4CA1FAHD1FFAR3HDAC3 | |
| Bicarbonate SCHEMBL14243920 | 0.94 | CA4 (0.42) | CA4CA1FAHD1FFAR3HDAC3 | |
| Bicarbonate SCHEMBL1515963 | 0.94 | CA4 (0.42) | CA4CA1FAHD1FFAR3HDAC3 | |
| Bicarbonate SCHEMBL43479 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1259818 | 0.88 | — | — | |
| Bicarbonate SCHEMBL9152986 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5359205 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL18789077 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-216189830-U | Base material embossing temperature-indicating heat shrinkage tape | 江苏达胜热缩防护用品有限公司 | 2022-04-05 | — | — | CN | disclosed |
| EP-2268854-B1 | METHOD FOR ELECTROCHEMICAL PLATING AND MARKING OF METALS | TENARIS CONNECTIONS LTD (VC) | 2014-11-05 | — | — | EP | disclosed |
| US-8257572-B2 | Method for electrochemical plating and marking of metals | TENARIS CONNECTIONS LIMITED (VC) | 2012-09-04 | — | — | US | disclosed |
| EP-2268854-A2 | METHOD FOR ELECTROCHEMICAL PLATING AND MARKING OF METALS | Tenaris Connections Limited (VC) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009118412-A2 | METHOD FOR ELECTROCHEMICAL PLATING AND MARKING OF METALS | TENARIS CONNECTIONS AG (LI) | 2009-10-01 | — | — | WO | disclosed |
| US-20090242410-A1 | METHOD FOR ELECTROCHEMICAL PLATING AND MARKING OF METALS | TENARIS CONNECTIONS AG (LIECHTENSTEIN CORPORATION) (LI) | 2009-10-01 | — | — | US | disclosed |
| EP-0124953-B1 | ACICULAR FERROMAGNETIC ALLOY PARTICLES FOR USE IN MAGNETIC RECORDING MEDIA | TODA KOGYO CORP. (JP) | 1987-03-25 | — | — | EP | disclosed |