Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 2/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609333 | 0.83 | HRH4 (0.56) | POLBMAPTTSHRHSP90AA1HPGD | |
| SCHEMBL13562274 | 0.81 | HRH4 (0.62) | — | |
| SCHEMBL11611858 | 0.74 | POLB (0.55) | POLBSMN1; SMN2HTTMAPTTSHR | |
| SCHEMBL18889291 | 0.74 | HRH4 (0.76) | POLBSMN1; SMN2KMT2A | |
| SCHEMBL25431128 | 0.72 | POLB (0.59) | POLBSMN1; SMN2PKMALPLPHGDH | |
| SCHEMBL30552687 | 0.72 | POLB (0.59) | POLBSMN1; SMN2PKMALPLPHGDH | |
| SCHEMBL4275417 | 0.71 | POLB (0.54) | POLBSMN1; SMN2MAPTALPL | |
| SCHEMBL3253717 | 0.71 | POLB (1.00) | POLBSMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL12864408 | 0.71 | POLB (0.62) | POLBSMN1; SMN2PKMHPGDKMT2A | |
| SCHEMBL6214896 | 0.70 | POLB (0.50) | POLBSMN1; SMN2HTTMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4084051-A | BACTERICIDES, HERBICIDES | STERLING DRUG INC. (US) | 1978-04-11 | — | — | US | claimed |
| US-4084051-A | BACTERICIDES, HERBICIDES | STERLING DRUG INC. (US) | 1978-04-11 | — | — | US | disclosed |
| US-4046775-A | 4,5-Dihalopyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-3963480-A | Herbicidal pyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1976-06-15 | — | — | US | disclosed |