Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 4/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609157 | 0.83 | POLB (0.55) | HPGDHSP90AA1POLBTSHRALPL | |
| SCHEMBL13562274 | 0.83 | HRH4 (0.62) | HRH4HRH3 | |
| SCHEMBL11611730 | 0.72 | MAP2K1 (0.50) | HRH4HRH3NPC1RAB9AHPGD | |
| SCHEMBL24896240 | 0.72 | HRH4 (0.78) | HRH4HRH3NPC1HPGDGLA | |
| SCHEMBL21235396 | 0.71 | HRH4 (0.55) | HRH4HRH3NPC1RAB9AHPGD | |
| SCHEMBL14484072 | 0.69 | HRH4 (0.79) | HRH4HRH3NPC1RAB9APLA2G7 | |
| SCHEMBL29944207 | 0.69 | HRH4 (0.76) | HRH4HRH3NPC1RAB9APOLB | |
| SCHEMBL2345954 | 0.69 | HRH4 (0.76) | HRH4HRH3NPC1RAB9APOLB | |
| SCHEMBL11607578 | 0.69 | DAO (0.39) | HPGDTSHRALDH1A1LMNAMAPT | |
| SCHEMBL2940426 | 0.69 | BLM (0.50) | HPGDTSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4084051-A | BACTERICIDES, HERBICIDES | STERLING DRUG INC. (US) | 1978-04-11 | — | — | US | disclosed |
| US-4046775-A | 4,5-Dihalopyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-3963480-A | Herbicidal pyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1976-06-15 | — | — | US | disclosed |