Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 8/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609220 | 0.99 | SIGMAR1 (0.60) | SIGMAR1GAADRD4 | |
| Hydrochloric Acid SCHEMBL11609456 | 0.98 | SIGMAR1 (0.59) | SIGMAR1GAADRD4 | |
| SCHEMBL11610249 | 0.83 | SIGMAR1 (0.58) | SIGMAR1DRD4 | |
| SCHEMBL11609616 | 0.82 | SIGMAR1 (0.70) | SIGMAR1DRD4 | |
| SCHEMBL11609709 | 0.82 | SIGMAR1 (0.58) | SIGMAR1DRD4 | |
| SCHEMBL11827664 | 0.81 | SIGMAR1 (0.57) | SIGMAR1GAADRD4 | |
| SCHEMBL11558925 | 0.81 | SIGMAR1 (0.57) | SIGMAR1DRD4 | |
| SCHEMBL2751444 | 0.81 | DRD4 (0.64) | GAADRD4 | |
| Hydrochloric Acid SCHEMBL11797848 | 0.81 | SIGMAR1 (0.56) | SIGMAR1GAADRD4 | |
| SCHEMBL3954720 | 0.80 | NPC1 (0.65) | GAADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087428-A | ANTIEMETICS | A. H. ROBINS COMPANY, INC. (US) | 1978-05-02 | — | — | US | disclosed |
| US-4073796-A | ANTIEMETIC | A. H. ROBINS COMPANY, INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4039678-A | N-(SUBSTITUTED-3-PYRROLIDINYL)-1-NAPHTHALENE CARBOXAMIDES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-08-02 | — | — | US | disclosed |
| US-4002757-A | ANTIEMETIC AGENTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-01-11 | — | — | US | disclosed |