Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GSDMD | P57764 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11610275 | 1.00 | MAPT (0.35) | MAPTKMT2ANPSR1MEN1MAPK1 | |
| SCHEMBL11609102 | 0.84 | CA12 (0.40) | MAPTKMT2ANPSR1MEN1MAPK1 | |
| SCHEMBL11609098 | 0.84 | CA12 (0.40) | MAPTKMT2ANPSR1MEN1MAPK1 | |
| SCHEMBL5239882 | 0.82 | MAPT (0.34) | MAPTKMT2ANPSR1MEN1MAPK1 | |
| SCHEMBL5239873 | 0.82 | MAPT (0.34) | MAPTKMT2ANPSR1MEN1MAPK1 | |
| SCHEMBL11607296 | 0.82 | MAPT (0.34) | MAPTKMT2ANPSR1MEN1MAPK1 | |
| SCHEMBL11607298 | 0.82 | MAPT (0.34) | MAPTKMT2ANPSR1MEN1MAPK1 | |
| SCHEMBL5239879 | 0.82 | MAPT (0.34) | MAPTKMT2ANPSR1MEN1MAPK1 | |
| SCHEMBL11610118 | 0.79 | ALDH1A1 (0.51) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL11610123 | 0.79 | ALDH1A1 (0.51) | MAPTKMT2AMEN1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075001-A | 3-Aminoisothiazole derivatives as herbicides | FMC CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |