Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605577 | 0.85 | ALDH1A1 (0.30) | ALDH1A1GAA | |
| SCHEMBL11605420 | 0.81 | IAPP (0.33) | ALDH1A1GAAKDM4E | |
| SCHEMBL11604274 | 0.80 | GSK3B (0.31) | GSK3B | |
| SCHEMBL11605629 | 0.78 | — | — | |
| SCHEMBL2359305 | 0.74 | AURKA (0.34) | ALDH1A1GAAKDM4EGSK3BAURKA | |
| SCHEMBL10335612 | 0.72 | DAO (0.40) | ALDH1A1GAAKDM4EGSK3B | |
| SCHEMBL8853391 | 0.71 | ALDH1A1 (0.42) | ALDH1A1GAACYP4F2CYP4A11KDM4E | |
| SCHEMBL29198937 | 0.70 | PDK2 (0.40) | ALDH1A1GAAKDM4EGSK3B | |
| SCHEMBL11610336 | 0.69 | ALDH1A1 (0.37) | ALDH1A1GAAKDM4EGSK3BMAPT | |
| SCHEMBL11576353 | 0.69 | ALDH1A1 (0.43) | ALDH1A1GAACDYLKDM4EGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080399-A | REACTING N-CHLOROTHIOPHTHALIMIDE WITH UNSATURATED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |