Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365284 | 0.87 | PKM (0.59) | PKMAPPKCNMA1TRPV1SMN1; SMN2 | |
| SCHEMBL13379289 | 0.84 | APP (0.66) | PKMAPPKCNMA1TRPV1SMN1; SMN2 | |
| SCHEMBL9365281 | 0.83 | APP (0.58) | PKMAPPKCNMA1TRPV1SMN1; SMN2 | |
| SCHEMBL3308366 | 0.82 | APP (0.64) | PKMAPPKCNMA1TRPV1SMN1; SMN2 | |
| SCHEMBL3308371 | 0.82 | APP (0.64) | PKMAPPKCNMA1TRPV1SMN1; SMN2 | |
| SCHEMBL3308373 | 0.82 | APP (0.64) | PKMAPPKCNMA1TRPV1SMN1; SMN2 | |
| SCHEMBL1503974 | 0.82 | APP (0.60) | PKMAPPKCNMA1TRPV1SMN1; SMN2 | |
| SCHEMBL10712446 | 0.82 | MAPT (0.64) | PKMAPPKCNMA1TRPV1SMN1; SMN2 | |
| SCHEMBL6080575 | 0.82 | APP (0.54) | PKMAPPKCNMA1TRPV1SMN1; SMN2 | |
| SCHEMBL6080567 | 0.82 | APP (0.54) | PKMAPPKCNMA1TRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099007-A | N,N-SUBSTITUTED 2,4,5-TRIKETOIMIDAZOLIDINES AND A PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |