Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611654 | 0.84 | GAA (0.41) | SIRT2SIRT1 | |
| SCHEMBL11609702 | 0.81 | IDO1 (0.46) | — | |
| SCHEMBL27784724 | 0.76 | EPHX1 (0.43) | — | |
| SCHEMBL11608083 | 0.74 | BCL2 (0.40) | — | |
| SCHEMBL11607956 | 0.72 | KDM4E (0.43) | — | |
| SCHEMBL11606953 | 0.71 | PTGS1 (0.33) | ESR1 | |
| SCHEMBL3807241 | 0.70 | EPHX1 (0.47) | — | |
| SCHEMBL368266 | 0.70 | EPHX1 (0.45) | — | |
| SCHEMBL11013763 | 0.69 | EPHX1 (0.50) | — | |
| Propane SCHEMBL8772781 | 0.67 | EPHX1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076814-A | DITHIOCARBAMIC ACID DERIVATIVES | SANKYO COMPANY LIMITED (JA) | 1978-02-28 | — | — | US | disclosed |