Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10748675 | 0.93 | ACHE (0.47) | EPHX1ACHE | |
| SCHEMBL10975756 | 0.93 | CA12 (0.40) | EPHX1FAAHACHECA12CA1 | |
| SCHEMBL17415987 | 0.91 | EPHX1 (0.39) | EPHX1FAAHACHECA12CA1 | |
| SCHEMBL27784724 | 0.91 | EPHX1 (0.43) | EPHX1FAAHACHECASP2TSHR | |
| SCHEMBL2495229 | 0.85 | CA12 (0.52) | EPHX1ACHECA12CA1CA2 | |
| SCHEMBL11203544 | 0.85 | ACHE (0.44) | EPHX1FAAHACHECA12CA1 | |
| SCHEMBL4349103 | 0.84 | — | — | |
| SCHEMBL17436874 | 0.83 | ACHE (0.53) | EPHX1ACHECA12CA1CA2 | |
| SCHEMBL17416108 | 0.83 | ACHE (0.53) | EPHX1ACHECA12CA1CA2 | |
| SCHEMBL17416051 | 0.83 | ACHE (0.53) | EPHX1ACHECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61271269-A | — | — | None | — | — | JP | disclosed |
| EP-1809726-B1 | USE OF 1,3-DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS | LANXESS SOLUTIONS US INC (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-1833951-B1 | DITHIOCARBAMYL ß-HYDROXY FATTY ACID ESTERS AS ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORP (US) | 2012-08-22 | — | — | EP | disclosed |
| US-8097731-B2 | Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidalzoles with epoxides as lubricant additives | CROMPTON CORPORATION (US) | 2012-01-17 | — | — | US | disclosed |
| US-8048832-B2 | 1,3 dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2011-11-01 | — | — | US | disclosed |
| EP-2314661-A1 | Lubricant and fuel compositions containing hydroxy polycarboxylic acid esters | Chemtura Corporation (US) | 2011-04-27 | — | — | EP | disclosed |
| EP-1654342-B1 | REACTION PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7696136-B2 | Lubricant compositions containing hydroxy carboxylic acid and hydroxy polycarboxylic acid esters | CROMPTON CORPORATION (US) | 2010-04-13 | — | — | US | disclosed |
| US-20090181870-A1 | 1,3 DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| US-7541319-B2 | 1,3-dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2009-06-02 | — | — | US | disclosed |
| WO-2001007543-A1 | IMIDAZOLE THIONE ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2000053703-A1 | CYCLIC THIOUREA ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-09-14 | — | — | WO | disclosed |
| US-5935913-A | EXTREME PRESSURE LUBRICANTS; ASHLESS AND NONPHOSPHORUS, ANTIWEAR, ANTIFATIGUE | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| JP-S61271269-A | PHOTO-SENSITIVE MONOMER AND PHOTO-SENSITIVE POLYMER | NIPPON PAINT CO LTD | 1986-12-01 | — | — | JP | disclosed |
| EP-0039440-B1 | MEDICINES CONTAINING SUBSTITUTED BENZOTHIAZOL-2-(3H)-ONES | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4353919-A | Analgesic and antipyretic pharmaceutical compositions containing a benzothiazol-2(3H)-one | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-10-12 | — | — | US | disclosed |
| US-4343618-A | Mothproofing agents | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1982-08-10 | — | — | US | disclosed |
| US-4303652-A | Fiber-reactive phosphorus mothproofing agents | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1981-12-01 | — | — | US | disclosed |
| EP-0039818-A1 | Substituted 2-(3H)-benzothiazolones, processes for their preparation, their utilization in the preparation of medicines and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1981-11-18 | — | — | EP | disclosed |
| EP-0039440-A1 | Medicines containing substituted benzothiazol-2-(3H)-ones | Dr. Karl Thomae GmbH (DE) | 1981-11-11 | — | — | EP | disclosed |