Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | NAMPT | P43490 | 16/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.60 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15573292 | 0.89 | NPC1 (0.63) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL20389232 | 0.86 | NAMPT (0.68) | NAMPTHTTROCK2ROCK1 | |
| SCHEMBL20389090 | 0.85 | NAMPT (0.62) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL27942157 | 0.85 | NPC1 (1.00) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL11848242 | 0.84 | KMT2A (1.00) | NPC1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL8212768 | 0.84 | NAMPT (0.84) | NPC1RAB9AKMT2AMEN1NAMPT | |
| SCHEMBL11748446 | 0.84 | NAMPT (0.73) | KMT2ANAMPTHTTGAAROCK2 | |
| SCHEMBL11621060 | 0.83 | HTT (0.76) | NPC1MAPTRAB9ANAMPTHTT | |
| SCHEMBL11647526 | 0.83 | ALDH1A1 (0.68) | NPC1MAPTRAB9AKMT2ANAMPT | |
| SCHEMBL20388975 | 0.83 | NAMPT (0.70) | NPC1RAB9AKMT2AMEN1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | disclosed |