Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 6/20 | 0.58 |
| ▸ | CTSL | P07711 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162107 | 0.81 | CTSV (0.58) | CTSVCTSLGAACYP1A2KDM4E | |
| SCHEMBL31457901 | 0.81 | CTSV (0.58) | CTSVCTSLGAACYP1A2KDM4E | |
| SCHEMBL4764681 | 0.81 | CTSV (0.67) | CTSVCTSLGAACYP1A2KDM4E | |
| SCHEMBL19211147 | 0.81 | CTSV (0.58) | CTSVCTSLGAACYP1A2KDM4E | |
| SCHEMBL31716577 | 0.81 | CTSV (0.58) | CTSVCTSLGAACYP1A2KDM4E | |
| Hydrochloric Acid SCHEMBL19211248 | 0.80 | CTSV (0.56) | CTSVCTSLGAACYP1A2KDM4E | |
| SCHEMBL4769993 | 0.79 | CTSV (0.77) | CTSVCTSLGAACYP1A2KDM4E | |
| SCHEMBL8499215 | 0.79 | CTSV (0.63) | CTSVCTSLGAACYP1A2KDM4E | |
| SCHEMBL472872 | 0.77 | CTSV (0.54) | CTSVCTSLGAACYP1A2KDM4E | |
| SCHEMBL9176968 | 0.77 | CTSV (0.57) | CTSVCTSLGAACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012622-A1 | BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |
| WO-2011012622-A1 | BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |