Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496137 | 1.00 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL11496134 | 1.00 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL11607955 | 1.00 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL10959939 | 1.00 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL11870497 | 1.00 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL11611279 | 1.00 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL11479964 | 0.92 | RAB9A (0.56) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL11483374 | 0.92 | RAB9A (0.56) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL11493146 | 0.86 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3HTR3E | |
| SCHEMBL11493141 | 0.86 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100355-A | 8β,12α-PGE2 -type compounds | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097675-A | 8β, 12α, 15β-PGF2α Compounds | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4095036-A | 8β,12α,15β-PGF2 β Compounds | THE UPJOHN COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4084063-A | PROSTAGLANDINS; ANTIULCER AGENTS, ANTICOAGULANTS, OXYTOCICS, DECONGESTANTS | THE UPJOHN COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-3987085-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |