Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616491 | 0.91 | ALDH1A1 (0.56) | SMN1; SMN2RAB9ANPC1RARBKDM4E | |
| SCHEMBL11612452 | 0.89 | ALDH1A1 (0.62) | SMN1; SMN2RAB9ANPC1RARBKDM4E | |
| SCHEMBL11611675 | 0.88 | MAPT (0.65) | SMN1; SMN2RAB9ANPC1RARBKDM4E | |
| SCHEMBL11612451 | 0.88 | MAPT (0.65) | SMN1; SMN2RAB9ANPC1RARBKDM4E | |
| SCHEMBL9745034 | 0.88 | MAPT (0.65) | SMN1; SMN2RAB9ANPC1RARBKDM4E | |
| SCHEMBL9745010 | 0.88 | MAPT (0.65) | SMN1; SMN2RAB9ANPC1RARBKDM4E | |
| SCHEMBL9695388 | 0.87 | RARB (0.58) | SMN1; SMN2RAB9ANPC1TP53RARB | |
| SCHEMBL10339235 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1TP53RARB | |
| SCHEMBL11612424 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1TP53RARB | |
| Hydrochloric Acid SCHEMBL11613426 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1TP53RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066570-A | OPTICAL CELLS, NEMATIC MIXTURES, LIQUID CRYSTALS | HOFFMAN-LA ROCHE INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-3997536-A | LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1976-12-14 | — | — | US | disclosed |