⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL364708 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL27653360 | 0.97 | CHRNB2 (0.65) | — | |
| Acetic Acid SCHEMBL9340454 | 0.93 | CHRNB2 (0.61) | — | |
| SCHEMBL18291857 | 0.90 | CHRNB2 (0.57) | — | |
| SCHEMBL4669293 | 0.90 | CHRNB2 (0.69) | — | |
| SCHEMBL25021936 | 0.90 | CHRNB2 (0.69) | — | |
| SCHEMBL52844 | 0.90 | CHRNB2 (0.69) | — | |
| SCHEMBL30306973 | 0.90 | CHRNB2 (0.69) | — | |
| Hydrochloric Acid SCHEMBL18275007 | 0.88 | CHRNB2 (0.55) | — | |
| SCHEMBL5216043 | 0.87 | CHRNB2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 871 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201915-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118146163-A | Benzimidazole derivative and preparation method thereof | 雅安职业技术学院 | 2024-06-07 | — | — | CN | claimed |
| CN-112939960-B | Carbonyl azetidine substituted NBD fluorescent dye and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2023-04-14 | — | — | CN | claimed |
| CN-113382982-B | Preparation method of siponimod | 广东东阳光药业有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-112939936-B | Carbonyl azetidine substituted naphthalimide fluorescent dye and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2022-11-15 | — | — | CN | claimed |
| CN-114835618-A | Preparation method of siponimod | 广东东阳光药业有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-113382982-A | Preparation method of siponimod | 广东东阳光药业有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-112939960-A | Carbonyl azetidine substituted NBD fluorescent dye and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2021-06-11 | — | — | CN | claimed |
| EP-0169602-B1 | PREPARATION OF N-SUBSTITUTED AZETIDINE 3-CARBOXYLIC ACID DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-03-01 | — | — | EP | claimed |
| EP-0169602-A1 | Preparation of n-substituted azetidine 3-carboxylic acid derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-01-29 | — | — | EP | claimed |
| EP-4747260-A1 | MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| US-12637458-B2 | Imidazo[1,2-a]pyridine compounds and their use in therapy | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2026-05-26 | — | — | US | disclosed |
| CN-122094935-A | Amide prodrugs and uses thereof | — | 2026-05-26 | — | — | CN | disclosed |
| US-12630548-B2 | Azetidine derivatives for the treatment of integrin associated diseases | THE UNIVERSITY OF NOTTINGHAM (GB) | 2026-05-19 | — | — | US | disclosed |
| EP-4739670-A1 | MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-13 | — | — | EP | disclosed |
| EP-0978279-A1 | Inhibitors of human glycogen phosphorylase | Pfizer Products Inc. (US) | 2000-02-09 | — | — | EP | disclosed |
| EP-0299513-B1 | Azetidine derivatives, compositions and their use | FIDIA GEORGETOWN INST (US) | 1994-10-05 | — | — | EP | disclosed |
| EP-0169602-B1 | PREPARATION OF N-SUBSTITUTED AZETIDINE 3-CARBOXYLIC ACID DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-03-01 | — | — | EP | disclosed |
| CN-86103728-A | Preparation reduces the method for the medicament of blood cholesterol levels | — | 1987-05-27 | — | — | CN | disclosed |
| EP-0169602-A1 | Preparation of n-substituted azetidine 3-carboxylic acid derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-01-29 | — | — | EP | disclosed |