Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.64 |
| ▸ | CDK1 | P06493 | 1/20 | 0.64 |
| ▸ | CDK4 | P11802 | 1/20 | 0.64 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.64 |
| ▸ | CCND1 | P24385 | 1/20 | 0.64 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.64 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433401 | 0.94 | CCNB2 (0.72) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A | |
| SCHEMBL29537861 | 0.94 | CCNB2 (0.72) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A | |
| SCHEMBL5628914 | 0.93 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A | |
| SCHEMBL23395754 | 0.93 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A | |
| Fluoride SCHEMBL27920182 | 0.92 | CCNB2 (0.70) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A | |
| SCHEMBL8371569 | 0.91 | KMT2A (0.66) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A | |
| SCHEMBL28304736 | 0.91 | CCNB2 (0.59) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A | |
| SCHEMBL9691233 | 0.91 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A | |
| SCHEMBL5628749 | 0.88 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A | |
| SCHEMBL2513030 | 0.88 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2HPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4120789-A | REACTION WITH A BIS- OR TRIS-GUANYLHYDRAZONIUM SALT, DECANTING | ANIC, S.P.A. (IT) | 1978-10-17 | — | — | US | disclosed |
| US-4076711-A | FOR TREATMENT OF PSORIASIS | SCHERING CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |