Oxalic Acid

Oxalic Acid

SCHEMBL11615013

CCN(CCCC1(c2ccc(OC)c(OC)c2)S(=O)(=O)CCCS1(=O)=O)CCc1ccc(OC)c(OC)c1.O=C(O)C(=O)O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 known ✓ P31645 1/20 0.39
OPRM1 known ✓ P35372 1/20 0.39
SCN1A P35498 1/20 0.72
SCN2A Q99250 1/20 0.72
SCN3A Q9NY46 1/20 0.72
L3MBTL1 Q9Y468 1/20 0.45
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 1/20 0.42
ADRB1 P08588 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
DRD2 P14416 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
DRD1 P21728 1/20 0.39
DRD4 P21917 1/20 0.39
SLC6A2 P23975 1/20 0.39
ADRA1D P25100 1/20 0.39
HTR1D P28221 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL11610568 0.86 SCN1A (0.85) SCN1ASCN2ASCN3AL3MBTL1KDM4E
Oxalic Acid SCHEMBL11611988 0.85 SCN1A (0.84) SCN1ASCN2ASCN3AL3MBTL1KDM4E
Oxalic Acid SCHEMBL11613683 0.85 SCN1A (0.80) SCN1ASCN2ASCN3AL3MBTL1KDM4E
Tiapamil SCHEMBL93936 0.84 SCN1A (1.00) SCN1ASCN2ASCN3AKDM4EHTR1A
Oxalic Acid SCHEMBL11608698 0.83 SCN1A (0.79) SCN1ASCN2ASCN3AL3MBTL1KDM4E
Tiapamil SCHEMBL635113 0.83 SCN1A (0.98) SCN1ASCN2ASCN3AKDM4EHTR1A
Oxalic Acid SCHEMBL11612228 0.82 SCN1A (0.77) SCN1ASCN2ASCN3AL3MBTL1KDM4E
Bromide SCHEMBL11615923 0.81 SCN1A (0.90) SCN1ASCN2ASCN3AKDM4EALDH1A1
SCHEMBL25861795 0.81 SCN1A (0.89) SCN1ASCN2ASCN3AKDM4EALDH1A1
Hydrochloric Acid SCHEMBL11607284 0.80 SCN1A (0.87) SCN1ASCN2ASCN3AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4127588-A Sulphur containing derivatives HOFFMANN-LA ROCHE INC. (US) 1978-11-28 US disclosed
US-4073797-A CORONARY DILATOR HOFFMANN-LA ROCHE INC. (US) 1978-02-14 US disclosed
US-4003914-A DITHIANE AND DISULFONE CORONARY DILATING AGENTS HOFFMANN-LA ROCHE INC. (US) 1977-01-18 US disclosed