Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615881 | 0.87 | FFAR4 (0.77) | FFAR4FFAR1FAAHALDH1A1 | |
| SCHEMBL11618654 | 0.87 | FFAR4 (0.77) | FFAR4FFAR1FAAHALDH1A1 | |
| SCHEMBL7550732 | 0.87 | FFAR4 (0.77) | FFAR4FFAR1FAAHALDH1A1 | |
| SCHEMBL11615905 | 0.87 | FFAR4 (0.77) | FFAR4FFAR1FAAHALDH1A1 | |
| SCHEMBL11743888 | 0.86 | FFAR4 (0.56) | FFAR4FFAR1KDM4CKDM4APHF8 | |
| SCHEMBL11615802 | 0.86 | FFAR4 (0.56) | FFAR4FFAR1ACACBACACAFAAH | |
| SCHEMBL11613594 | 0.85 | FFAR4 (0.69) | FFAR4FFAR1FAAHTBXA2RPTGFR | |
| SCHEMBL11617329 | 0.85 | FFAR4 (0.74) | FFAR4FFAR1FAAHALDH1A1 | |
| SCHEMBL11659103 | 0.84 | FFAR4 (0.46) | FFAR4FFAR1KDM4CKDM4APHF8 | |
| SCHEMBL11619689 | 0.83 | FFAR4 (0.75) | FFAR4FFAR1FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097504-A | 11,12-Secoprostaglandins | MERCK & CO., INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4092356-A | 11,12-Secoprostaglandins | MERCK & CO., INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4066692-A | 11,12-SECOPROSTAGLANDINS | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4059601-A | VASODILATION, HYPOTENSIVE, ANTITHROMBOSIS | MERCK & CO., INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4059602-A | HYPOTENSIVE, VASODILATION, ANTITHROMBOSIS | MERCK & CO., INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-3991087-A | RENAL VASODILATORS, HYPOTENSIVE AGENTS, ANTITHROMBOTICS | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |