Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730477 | 0.82 | CYP3A4 (0.56) | KDM4EALDH1A1TSHRTDP1HMGCR | |
| SCHEMBL10730464 | 0.82 | CYP3A4 (0.56) | KDM4EALDH1A1TSHRTDP1HMGCR | |
| SCHEMBL1039129 | 0.78 | ALDH1A1 (0.72) | KDM4EALDH1A1TSHRTDP1HMGCR | |
| SCHEMBL2954181 | 0.78 | TAAR1 (0.56) | KDM4EALDH1A1CYP3A4TAAR1MAPT | |
| SCHEMBL12621133 | 0.77 | HMGCR (0.73) | KDM4EALDH1A1TSHRTDP1HMGCR | |
| SCHEMBL13498711 | 0.77 | HMGCR (0.73) | KDM4EALDH1A1TSHRTDP1HMGCR | |
| SCHEMBL13324430 | 0.77 | HMGCR (0.73) | KDM4EALDH1A1TSHRTDP1HMGCR | |
| SCHEMBL27515962 | 0.74 | TAAR1 (0.52) | KDM4EALDH1A1TSHRTDP1HMGCR | |
| SCHEMBL27575257 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1TSHRTDP1HMGCR | |
| SCHEMBL14135320 | 0.74 | CYP3A4 (0.47) | KDM4EALDH1A1TSHRTDP1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105695-A | LEARNING ENHANCEMENT, IMPROVES MENTAL ALERTNESS OF GERIATRICS | BRISTOL-MYERS COMPANY (US) | 1978-08-08 | — | — | US | disclosed |