SCHEMBL11615149

SCHEMBL11615149

Sc1nc(S)nc(SCc2ccccc2)n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
NPC1 O15118 3/20 0.59
HSD17B10 Q99714 1/20 0.57
HSP90AA1 P07900 1/20 0.53
ALOX15 P16050 2/20 0.50
METAP2 P50579 2/20 0.49
METAP1 P53582 1/20 0.49
ALDH1A1 P00352 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 1/20 0.49
MAPT P10636 1/20 0.49
HIF1A Q16665 1/20 0.49
ROCK2 O75116 1/20 0.47
MAP4K4 O95819 1/20 0.47
PRKX P51817 1/20 0.47
AURKB Q96GD4 1/20 0.47
CLK4 Q9HAZ1 1/20 0.47
SGK2 Q9HBY8 1/20 0.47
MAP4K5 Q9Y4K4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13752162 0.85 RAB9A (0.70) RAB9ASMN1; SMN2NPC1HSD17B10HSP90AA1
SCHEMBL13400080 0.82 RAB9A (0.47) RAB9ASMN1; SMN2NPC1HSP90AA1MAPT
SCHEMBL22655232 0.82 ABCB1 (0.54) RAB9ASMN1; SMN2NPC1ALDH1A1CYP1A2
SCHEMBL12090278 0.81 RAB9A (0.62) RAB9AMETAP2ALDH1A1MAPTL3MBTL1
SCHEMBL10561244 0.78 RAB9A (0.66) RAB9ASMN1; SMN2NPC1HSD17B10METAP2
SCHEMBL12090276 0.77 DAO (0.48) RAB9ASMN1; SMN2NPC1HSP90AA1CYP1A2
SCHEMBL5888974 0.76 RAB9A (0.59) RAB9ASMN1; SMN2NPC1HSD17B10HSP90AA1
SCHEMBL5450296 0.74 RAB9A (0.68) RAB9ASMN1; SMN2NPC1HSD17B10HSP90AA1
SCHEMBL489903 0.74 RAB9A (0.62) RAB9ASMN1; SMN2NPC1HSD17B10HSP90AA1
SCHEMBL10882423 0.74 RAB9A (1.00) RAB9ASMN1; SMN2NPC1HSD17B10HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11851529-B2 Triazine ring-containing polymer, and thermoplastic article and optical part including same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-12-26 US disclosed
US-11827750-B2 Triazine ring-containing polymer, and thermoplastic resin, article, and optical part including same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-28 US disclosed
US-11814482-B2 Triazine ring-containing polymer, and thermoplastic article and optical part including same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-14 US disclosed
US-20210163682-A1 TRIAZINE RING-CONTAINING POLYMER, AND THERMOPLASTIC ARTICLE AND OPTICAL PART INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-06-03 US disclosed
US-20200362112-A1 TRIAZINE RING-CONTAINING POLYMER, AND THERMOPLASTIC ARTICLE AND OPTICAL PART INCLUDING SAME NATIONAL UNIVERSITY CORPORATION IWATE UNIVERSITY (JP) 2020-11-19 US disclosed
US-9556294-B2 Magnetic particle-polymer hybrid materials with functionalized polymers derived from norbornenyl reagents THE UNIVERSITY OF KANSAS (US) 2017-01-31 US disclosed
US-20150175725-A1 MAGNETIC PARTICLE-POLYMER HYBRID MATERIALS WITH FUNCTIONALIZED POLYMERS DERIVED FROM NORBORNENYL REAGENTS THE UNIVERSITY OF KANSAS (US) 2015-06-25 US disclosed
US-9035003-B2 High capacity magnetic nanoparticles as supports for reagents and catalysts THE UNIVERSITY OF KANSAS (US) 2015-05-19 US disclosed
US-9029457-B2 Silica-supported oligomeric hybrid materials THE UNIVERSITY OF KANSAS (US) 2015-05-12 US disclosed
US-20120226007-A1 HIGH CAPACITY MAGNETIC NANOPARTICLES AS SUPPORTS FOR REAGENTS AND CATALYSTS THE UNIVERSITY OF KANSAS (US) 2012-09-06 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed