Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615297 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11619326 | 0.83 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11619320 | 0.83 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11618414 | 0.79 | KDM4E (0.36) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11618410 | 0.79 | KDM4E (0.36) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11618739 | 0.76 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11614839 | 0.72 | KDM4E (0.56) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9724289 | 0.72 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11613679 | 0.71 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11619396 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |