Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11578742 | 1.00 | CTRC (0.46) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL11574664 | 0.88 | PRSS1 (0.39) | CTRCPPARGHDAC1HDAC11HDAC8 | |
| SCHEMBL11617528 | 0.88 | PRSS1 (0.39) | CTRCPPARGHDAC1HDAC11HDAC8 | |
| SCHEMBL9814953 | 0.80 | PPARA (0.60) | PPARGPPARAMAPT | |
| SCHEMBL16667503 | 0.80 | GLA (0.35) | CTRCPPARGHDAC1HDAC11HDAC8 | |
| SCHEMBL28882503 | 0.80 | GLA (0.35) | CTRCPPARGHDAC1HDAC11HDAC8 | |
| SCHEMBL11531304 | 0.78 | CTRC (0.64) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL6342298 | 0.78 | CTRC (0.64) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL22828775 | 0.78 | CTRC (0.64) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL4002165 | 0.78 | CTRC (0.64) | CTRCPPARGPTGESALOX5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086417-A | ANTILEUKEMIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-04-25 | — | — | US | disclosed |