SCHEMBL11615489

SCHEMBL11615489

Cc1cccc2c(C)c3ccccc3cc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
CYP2A6 P11509 5/20 0.60
CYP1A2 P05177 8/20 0.57
HSD17B10 Q99714 4/20 0.57
HPGD P15428 4/20 0.57
TSHR P16473 4/20 0.50
HIF1A Q16665 2/20 0.45
CYP3A4 P08684 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPK1 P28482 1/20 0.45
CASP1 P29466 1/20 0.45
RAB9A P51151 1/20 0.45
CASP7 P55210 1/20 0.45
ATM Q13315 1/20 0.45
CYP1B1 Q16678 1/20 0.44
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 2/20 0.38
GAA P10253 2/20 0.38
ACHE P22303 2/20 0.38
TYMP P19971 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6885497 0.88 CYP1A2 (0.63) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD
SCHEMBL21918532 0.84 CYP1A2 (0.63) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD
SCHEMBL119090 0.81 CYP1A2 (0.56) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD
SCHEMBL29360084 0.81 CYP1A2 (0.56) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD
SCHEMBL598230 0.81 CYP1A2 (0.65) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD
SCHEMBL10524314 0.81 CYP1A2 (0.55) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD
SCHEMBL598175 0.81 CYP1A2 (0.65) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD
SCHEMBL20788832 0.80 HSD17B10 (0.58) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD
SCHEMBL130783 0.79 CYP1A2 (0.69) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD
SCHEMBL14596478 0.79 ALDH1A1 (0.56) ALDH1A1CYP2A6CYP1A2HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106336414-B A kind of nitogen-contained heterocycle derivant and its application in organic electroluminescence device 长春海谱润斯科技有限公司 2018-08-17 CN disclosed
CN-106336414-A Nitrogenous heterocyclic derivative, and application thereof in organic electroluminescent devices 长春海谱润斯科技有限公司 2017-01-18 CN disclosed
US-20100236936-A1 Aqueous,alkaline,cyanide-free bath for the galvanic deposition of zinc and zinc alloy coatings ATOTECH DEUTSCHLAND GMBH (DE) 2010-09-23 US disclosed
US-20100155257-A1 Aqueous, alkaline, cyanide-free bath for the galvanic deposition of zinc alloy coatings ATOTECH DEUTSCHLAND GMBH (DE) 2010-06-24 US disclosed
US-4076830-A TRANQUILIZERS, ANALGESICS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-02-28 US disclosed