Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11612370 | 0.92 | TSHR (0.31) | TSHR | |
| SCHEMBL36807 | 0.87 | — | — | |
| SCHEMBL11799057 | 0.82 | TSHR (0.35) | TSHR | |
| SCHEMBL8649574 | 0.78 | — | — | |
| SCHEMBL7718061 | 0.78 | — | — | |
| SCHEMBL9777975 | 0.77 | TSHR (0.41) | TSHR | |
| SCHEMBL11303366 | 0.76 | — | — | |
| SCHEMBL5796156 | 0.73 | — | — | |
| SCHEMBL9725542 | 0.73 | TDP1 (0.33) | — | |
| SCHEMBL4544255 | 0.72 | CYP3A4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115635-A | Process for the production of poly (allyl halide allyl alcohol) polymer | BLOUNT DAVID H | 1978-09-19 | — | — | US | claimed |
| US-4115635-A | Process for the production of poly (allyl halide allyl alcohol) polymer | BLOUNT DAVID H | 1978-09-19 | — | — | US | disclosed |